Ebola survivors suffer from severe neurological problems
Researchers have shed new light on the psychiatric and neurological problems that Ebola survivors can suffer from, and call for more specialist support for the most severely affected patients.
View ArticleBroadly acting antibodies found in plasma of Ebola survivors
Recent Ebola virus disease (EVD) outbreaks highlight the need for licensed treatments. ZMapp, an experimental therapy, has shown promise in a clinical trial, but targets only one of five known species...
View ArticlePotent antibodies against three Ebola viruses
Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal...
View ArticlePathways Ebola virus uses to enter cells
A new study is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to establish replication.
View ArticleEbola virus experts discover powerful, new approach for future therapeutics
A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists.
View ArticleExperts highlight ebola vaccine progress and suggest next steps
Despite promising advances, important scientific questions remain unanswered in the effort to develop a safe and effective Ebola vaccine, according to members of an international Ebola research...
View ArticleRapid development in Central Africa increases the risk of infectious disease...
The Central Africa region is experiencing rapid urbanization, economic growth and infrastructure development. These changes, while generally positive, also make the region more vulnerable to infectious...
View ArticleHow the human immune system protects against Ebola
'The current approach for treatment of filovirus infections with antibody cocktails tested in animal models utilizes the principle of targeting of non-overlapping epitopes. Our study suggests that...
View ArticleMechanism of Marburg virus sexual transmission identified in nonhuman primates
New research elucidates the mechanism of sexual transmission of filoviruses, which have been shown to persist in the testes and other immune privileged sites. Sexual transmission of filoviruses was...
View ArticleRare antibodies show scientists how to neutralize the many types of Ebola
Two new studies are bringing Ebola virus's weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection -- not only for...
View ArticleText messages quickly track health care use during Ebola outbreak
A new study used text message surveys to determine in real time how people used maternal health services during a recent Ebola outbreak and measured a drop in hospital-based births during the outbreak.
View ArticleDNA vaccine against Ebola virus shows potent and long-term efficacy in...
A novel synthetic DNA vaccine developed based on technology pioneered and offers complete protection from Zaire Ebolavirus (EBOV) infection in promising preclinical research.
View ArticleLassa fever vaccine shows promise and reveals new test for immunity
A new Lassa fever and rabies vaccine shows lasting immunity and suggests a new way to test for protection.
View ArticleDurable immune response to 3 experimental Ebola vaccines: Broad vaccine...
In the midst of an increasingly volatile Ebola outbreak in the Democratic Republic of Congo, a new study finds that the immune response generated by three experimental Ebola vaccines -- including one...
View ArticleSynthetic DNA-delivered antibodies protect against Ebola in preclinical studies
Scientists have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results showed that DMAbs were...
View ArticleModified malaria drug proven effective at inhibiting Ebola
Researchers have discovered that certain derivatives of amodiaquine, a medication typically used to treat malaria, could provide a new therapeutic approach to treating patients infected with Ebola...
View ArticleNew interactions between Ebola virus and human proteins discovered
Several new connections have been discovered between the proteins of the Ebola virus and human host cells, a finding that provides insight on ways to prevent the deadly Ebola virus from reproducing and...
View ArticleEbola-fighting protein discovered in human cells
Researchers have discovered a human protein that helps fight the Ebola virus and could one day lead to an effective therapy against the deadly disease, according to a new study. The newly discovered...
View ArticleExperimental antibody 'cocktail' protects animals from three deadly Ebola...
Scientists have developed a combination of monoclonal antibodies that protected animals from all three Ebola viruses that cause human disease. The antibody 'cocktail,' called MBP134, is the first...
View ArticleAnother piece of Ebola virus puzzle: Host and virus protein interaction
A team of researchers have discovered the interaction between an Ebola virus protein and a protein in human cells that may be an important key to unlocking the pathway of replication of the killer...
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